Sponsor Spotlight: ThreatLocker

ThreatLocker sets new Zero Trust standard with field-tested innovation 

We're proud to spotlight ThreatLocker, a cybersecurity powerhouse that's been our valued partner for over a year. ThreatLocker delivers cutting-edge Zero Trust solutions that put IT professionals back in the driver's seat.

"ThreatLocker is proud to have partnered with TWiT for over a year. Their hosts are some of the most respected voices in technology and cybersecurity, and their audience reflects that same level of expertise and engagement. It's been a natural and rewarding alignment—working together to elevate the conversation around real security solutions and empower IT professionals to take control in an ever-evolving threat landscape," explains David Coovert, Senior Strategist for Industry Media at ThreatLocker.

Behind this innovative company is Danny Jenkins, CEO and co-founder of ThreatLocker, a recognized leader in cybersecurity innovation who is still hands-on, still in the trenches. With decades of experience protecting enterprise networks, Danny's mission is simple but bold: put IT back in control. 

For years, the cybersecurity industry focused on chasing threats. That meant IT pros were always on alert, waiting for that 2 a.m. crisis. What distinguishes ThreatLocker is a core principle: applications are denied by default, so threats have a much harder time getting in. With ThreatLocker, the surface area of each endpoint is significantly smaller. It's a transformative shift that brings peace of mind for IT pros.     

"Working with ThreatLocker has changed the way we think about cybersecurity. It's not just protection—it's control," says one ThreatLocker partner. ThreatLocker delivers a Zero Trust endpoint security platform that blocks unknown applications, contains lateral movement, and prevents unauthorized access before threats can do damage. In other words, real security starts with default deny.

CISO lauds real-world Zero Trust progress

A CISO at a Mid-Market Enterprise praised the advancements made by ThreatLocker: "ThreatLocker has made Zero Trust achievable, not just a buzzword." At Zero Trust World 2025, ThreatLocker accomplished even more, unveiling a comprehensive suite of solutions revolutionizing cybersecurity management: 

• ThreatLocker Insights leverages data from millions of endpoints to provide real-time intelligence for swift security decisions.
• Before deployment, ThreatLocker Patch Management consolidates and tests all software updates through its Cyber Hero® Team.
• ThreatLocker User Store offers pre-approved applications with automatic policy creation, while ThreatLocker Web Control provides seamless web access management without integration headaches.
• ThreatLocker Cloud Control protects Microsoft 365 tenants against phishing and token theft, and the ThreatLocker Detect Dashboard compiles all incident data into actionable visualizations with one-click resolutions.

Hospital blocks infiltration with ThreatLocker

The real-world impact of ThreatLocker goes beyond features. It's proven in actual cyberattacks. Cybercriminals recently used stolen domain admin credentials to infiltrate a hospital network, aiming to deploy remote access tools, steal sensitive data, and unleash ransomware. When they reached this hospital protected by ThreatLocker, their plan collapsed completely. Application Allowlisting blocked their unauthorized software, Storage Control prevented data access, and the attackers found themselves unable to deploy tools, spread through the network, or execute anything. Watch the breakdown of this real-world attack and see precisely how ThreatLocker stopped what could have been a devastating ransomware incident.

An IT Director at a global manufacturing firm explains, "ThreatLocker gives us peace of mind by eliminating unknowns. We've gone from being reactive to completely in control."

Ready to put IT back in control? ThreatLocker offers easy deployment and 24/7 U.S.-based support. Visit threatlocker.com/twit to get a free 30-day trial and learn more about how ThreatLocker can help mitigate unknown threats and ensure compliance.