Running time: 1:06:11

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Host: Marc Pelletier

Guest: Dr. Evangelos Michelakis, MD, FACC, FAHA

Our guest, Dr. E. Michelakis, published an extremely interesting paper on how a very inexpensive drug called DCA, could potentially tackle multiple forms cancer including lung, brain, and breast cancer. Otherwise known as dichlororoacetate, it has been used for decades to treat the metabolic disorder Lactic Acidosis and other inherited mitochondrial metabolic diseases. It can seemingly switch the unique metabolism of cancer cells back to normal - triggering a process referred to as Apoptosis - a form of programmed cell death. This is an AMAZING science versus cancer story - BUT:

Please listen to the disclaimer at the end of the show, I did keet the tape rolling and our discussion moved towards the potential missuse of DCA outside the context of clinical trials. So again - really - please listen to Dr. Michelakis' final comments if your thinking of using DCA.

Some interesting links:

Official University of Alberta DCA Website
DONATIONS
Dr. Michelakis' paper in Cancer Cell
Scientific Review: “Metabolic Targeting as an Anti-cancer Strategy; Dawn of a New Era?”

Our book of the week, reviewed by Dr. Ginger Campbell from the Brain Science Podcast, is A Short History of Nearly Everything by Bill Bryson. For your free audio book visit Audible.com/Biotech.

Thanks to Cachefly for providing the bandwidth for this netcast.

Also thanks to Philippe Pelletier and Will Hall for the great opening and closing themes AND Matthew McInerney for the cool FiB Desktops.